The Facts

Some Facts About Childhood Cancer

  1. Cancer remains the top disease-related cause of death among children and adolescents aged 1-19 in the U.S., with 1 in 264 expected to develop cancer by age 20.
  2. Globally, a child is diagnosed with cancer every two minutes, totaling approximately 300,000 diagnoses annually.
  3. The average age at diagnosis is six, though childhood cancers can be diagnosed at any age, from infants to young adults.
  4. A staggering 80% of childhood cancer cases occur in developing countries, underscoring the need for global collaborative efforts in research and treatment.
  5. Acute lymphoblastic leukemia (ALL) is the most prevalent childhood cancer. Survival rates have dramatically improved from the 1950s, with about 90% now surviving the most common type of ALL, though other forms have much lower survival rates.
  6. At diagnosis, cancer has already metastasized in 80% of affected children, necessitating immediate treatment—unlike many adult cancers, which are often detected earlier.
  7. Insights from pediatric cancer research have significantly influenced adult cancer treatments, including the development of combination chemotherapy.
  8. Childhood cancer encompasses over a dozen major types and hundreds of subtypes, with the rarer forms collectively representing about 30% of cases.
  9. In the U.S., 20% of children diagnosed with cancer do not survive, and survivors often face lifelong health battles.
  10. Research funding for childhood cancer is limited, making up less than 4% of all cancer research funding allocated by major health organizations.
  11. Childhood cancer treatments can lead to secondary health issues later in life, including heart, lung, and cognitive impairments, emphasizing the need for tailored and less toxic treatment protocols.
  12. Treatment advances have increased the 5-year survival rate for childhood cancers significantly over the past few decades.
  13. Despite improvements in treatment, disparities exist in survival rates among different demographic groups.
  14. Late effects of cancer treatment can affect childhood cancer survivors throughout their lives, necessitating ongoing medical care.
  15. Genetic factors play a role in approximately 10% of childhood cancers, highlighting the importance of genetic research.
  16. Brain tumors are the second most common type of cancer in children, presenting unique challenges in treatment and recovery.
  17. The psychological impact of cancer on children and their families can be profound, requiring comprehensive support services.
  18. Public awareness and funding for childhood cancer research are critical in driving advancements in treatment and support.
  19. The cost of cancer treatment can be overwhelming for families, often leading to significant financial hardship.
  20. International collaboration in research and treatment protocols is vital for addressing the global challenge of childhood cancer.